Germline Quality Control: eEF2K Stands Guard to Eliminate Defective Oocytes
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چکیده
منابع مشابه
Germline quality control: eEF2K stands guard to eliminate defective oocytes.
The control of germline quality is critical to reproductive success and survival of a species; however, the mechanisms underlying this process remain unknown. Here, we demonstrate that elongation factor 2 kinase (eEF2K), an evolutionarily conserved regulator of protein synthesis, functions to maintain germline quality and eliminate defective oocytes. We show that disruption of eEF2K in mice red...
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ژورنال
عنوان ژورنال: Developmental Cell
سال: 2014
ISSN: 1534-5807
DOI: 10.1016/j.devcel.2014.01.027